Pereira, J., & Phan, T. (2004). Management of bleeding in patients with advanced cancer. Oncologist, 9, 561–570.

DOI Link

Purpose & Patient Population

PURPOSE: To review an article with associated continuing medical education on the management of bleeding in patients with advanced cancer. Local interventions include suggestions for wound management.

Results Provided in the Reference

  • Includes eight references specific to dressing interventions for bleeding

Guidelines & Recommendations

  • Packing with or without pressure—nose, vagina, rectum; packing swabs can contain hemostatic agents (i.e., acetone in vagina or cocaine in nose)
  • Use nonadherent dressings.
  • Frequency of dressing changes minimized to prevent trauma
  • Topical dressings/ interventions include thromboplastin to control bleeding topically; absorbable gelatin topically or in the nose, rectum, or vagina; fibrin sealants; and collagen
  • Vasoconstricting or cauterizing agents: epinephrine, silver nitrate, formalin, and alum

Limitations

  • Peer-reviewed journal intended to disseminate practice interventions
  • Acknowledges that interventions are based on case studies and there is an overall lack of evidence