CML Physical Presentation
The typical physical presentation of CML is that of splenomegaly, which may present as minimal to profound. It is often first diagnosed through a routine examination, as patients may not complain of any presenting symptoms. In about 10% of patients, splenomegaly is absent at presentation (National Cancer Institute, 2011b). When the symptoms do occur, they tend to develop gradually and are consistent with many other diseases. Symptoms include
- Shortness of breath upon exertion
- Pale skin
- Discomfort in warm temperatures
- Unexplained weight loss
- Feeling full after eating a small amount of food
- Night sweats.